Artykuły naukowe (WCh)
Permanent URI for this collection
Browse
Browsing Artykuły naukowe (WCh) by Author "Kuciński, Krzysztof"
Now showing 1 - 2 of 2
Results Per Page
Sort Options
Item Base-catalyzed addition of silylacetylenes to ketones: a route to protected tertiary propargyl alcohols(The Royal Society of Chemistry, 2023-05-07) Kuciński, Krzysztof; Łuczak, Alicja; Mankouski, Aliaksei; Hreczycho, GrzegorzThe base-catalyzed addition of alkynylsilanes to ketone derivatives enables the formation of various silyl-protected propargylic alcohols. Commercially available and inexpensive potassium bis(trimethylsilyl)amide (KHMDS) serves as an efficient transition metal-free catalyst and permits the functionalization of a variety of derivatives, including pharmaceuticals and biorelevant compounds. Overall, the presented system complements classical routes to protected tertiary propargylic alcohols that mainly rely on stoichiometric processes or fluoride-mediated reactions.Item Electrifying synthesis of organosilicon compounds – from electrosynthesis to electrocatalysis(The Royal Society of Chemistry, 2023-02-02) Kuciński, KrzysztofOccasionally, a synthetic strategy is developed that seems to be a game changer. Not long ago, mechanochemistry or ionic liquids were intensively explored to afford organosilicon compounds. These and other approaches still offer benefits and influence the development of this field. Electrochemistry is currently a new synthetic strategy. Despite its long history, electrosynthesis or electrocatalysis have not become routine procedures in the synthesis of organosilicons. One may justifiably ask why. Accessibility and reproducibility are one of the challenges of electrochemical approaches. However, recent developments in the field of electrified organic synthesis have provided new insights and allowed electrochemistry to become an approachable tool. In this perspective article, several notable contributions to the electrochemical synthesis of organosilicon compounds are highlighted.