'Laboratory investigations of diclofenac migration in saturated porous media - a case study

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Date

2019-12

Authors

Okońska, Monika
Marciniak, Marek
Zembrzuska, Joanna
Kaczmarek, Mariusz

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Publisher

Instytut Geologii UAM

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Abstract

At present, concentrations of pharmaceuticals in surface and ground waters are low; however, even low concentrations of certain substances may prove very harmful. One of such pharmaceutical drugs is diclofenac, a popular non-steroidal anti-inflammatory drug (NSAID). For this reason, it is important to determine its mobility in groundwater and to estimate parameters of migration. Authors conducted column tests for two porous media: an artificial one, consisting of glass granules, and a natural one, i.e., sandur sand obtained from a site north of the city of Poznań (Poland). During the test, impulse breakthrough curves of chloride ions and diclofenac were recorded. The results were used to identify a specific sorption model and to determine values of migration parameters. Solutions of the inverse problem using optimisation methods and of equations of mathematical migration models were carried out in a MATLAB environment. Based on test results, the mobility of diclofenac is shown to be very high and comparable to that of chloride ions. The tests also revealed a slight and irreversible sorption of diclofenac on grains of both porous media.

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Keywords

non-steroidal anti-inflammatory drug, column test, parameter estimation, optimisation method, MATLAB

Citation

Geologos, 2019, 25, 3, s.213-223

ISBN

978-83-232187-4-6

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Rights Creative Commons

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Uniwersytet im. Adama Mickiewicza w Poznaniu
Biblioteka Uniwersytetu im. Adama Mickiewicza w Poznaniu
Ministerstwo Nauki i Szkolnictwa Wyższego