Browsing by Author "Czapla, Zbigniew"
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Item Appraisal of changeability of the EMN index with regard to lifestyle of the basis of daily examination(Palacky University Olomouc, 1998) Czapla, ZbigniewItem Assessment of Physical Growth in Children with Congenital Adrenal Hyperplasia (CAH)(2008) Czapla, Zbigniew; Niedziela, Marek; Cieślik, JoachimThe study is an attempt to assess the degree and direction of deviations in two physical development traits: body weight and height in children with congential adrenal hyperplasia (CAH), as compared to the norm. The pattern of growth of the studied traits in children with CAH is significantly different than an average pattern for normal children. A new research approach used to investigate the problem of developmental disorders in children with CAH revealed that both body height and weight - regardless of the sex - in successive stages (prepubertal, pubertal and postpubertal) of ontogenetic development tend to have progressively lower mean values as compared to the norm, and that differences between these values in the analyzed stages are statistically significant (p<0.01).Item Biologia starzenia w świetle metody mikroelektroforezy wewnątrzkomórkowej - EMN(Akademia Wychowania Fizycznego Józefa Piłsudskiego, 2001) Czapla, ZbigniewItem Charakterystyka elektroforetycznej ruchliwości jąder komórkowych (EMN) u trenujących dziewcząt(Tower Press Sopot, 2006) Czapla, Zbigniew; Szczepanowska, EwaMetabolic activity of cells could be describe by changes of an index of Electrophoretic Mobility of Cell Nuclei (EMN) in epithelium cells. The examined group (N = 33) consisted of female juniors practicing rowing. In this study 3 exercise tests of an increasing intensity up to: anaerobic threshold, maximal oxygen uptake and supermaximal intensity were applied. Values of EMN index reflected an influence of physical exercise on metabolic status of an organism determining a concentration of acidic intermediates. Changes of EMN index were connected with the metabolic threshold of anaerobic processes indicating the oxygen potential of an organism. EMN index could be used as an additional parameter to evaluate physiological changes under the influence of physical exercise. In an aspect of the level of performance it could be helpful in evaluation of physiological changes during training process.Item Electrophoretic Mobility of Cell Nuclei (EMN) index — relation to biological and physical properties of the cell(Polskie Towarzystwo Antropologiczne, 1998) Czapla, Zbigniew; Cieślik, JoachimThe authors describe certain physical and biological properties of cell and resulting electrical and electrokinetic properties, directly or indirectly related with the Electrophoretic Mobility of Cell Nuclei (EMN) index. This index, may become a new criterion in the estimation of the biological age, irrespective of the stage of the ontogenesis.Item Excessive physical exercise in tourism and recreation and its metabolic effects(2008) Szczepanowska, Ewa; Umiastowska, Danuta; Czapla, ZbigniewAn excessive physical exercise destructively influences on humans. This question has now a not overpriced meaning because there are more and more popular extreme kinds of tourism, recreation and sport, and far shifting limits of results attained in elite sport, and there are wider range of time and loads of professional work, which can lead even to work holism. If compare human body organization to not oversized device or building construction, one has to say that human body is in the same way subjected to stress, it means energy expenditure. A subjection to permanent stress without a full recovery can cause an abiding change of a metabolism regulation level. It means strain of this regulation. It is a shift within a genetically programmed range of homeostasis and a change of biological requirements of human body subordinative to maintenance a relative and very labile metabolic balance. However, it is not free. Each physical exercise is a download of an energetic credit from human body energetic substrates. If this credit is too high, it can cause a dysfunction of some functional spheres of a human being and can turn into an overtraining status. Usually, it manifests in suppression of the most energy-consuming function, it means reproductive function. It occurs in both genders. Then, this question is very complicated from the psychic sphere of human being, too.Item Kształtowanie się wskaźnika EMN w ontogenezie u osób palących i alkoholików(Uniwersytet Zielonogórski, 2002) Czapla, ZbigniewItem New approach to assessment of aging processes at the cellular level by NMR spectroscopy(Ośrodek Wydawnictw Naukowych Polish Academy of Sciences, 2000) Czapla, Zbigniew; Fojud, Zbigniew; Cieślik, Joachim; Jurga, StefanThe paper presents results of the proton relaxation time T1 measurements by 1H NMR for oral epithelium samples taken from 320 subjects, men and women, in different age, from 19 to 95 year old. The times of nuclear magnetic relaxation T1 were found to be correlated with the age of the subjects.Item O pewnych osobliwościach biologicznego i psychicznego pojmowania rozwoju(Kieleckie Towarzystwo Naukowe, 1997) Czapla, ZbigniewItem O pewnych wybranych kryteriach "normy" w psychologii i psychiatrii(Wydawnictwo Uniwersytetu Łódzkiego, 2000) Czapla, ZbigniewItem Phenomenon of electrophoretic mobility of cell nuclei (EMN) as a consequence of biological and physical properties of the cell(Palacky University Olomouc, 1998) Czapla, ZbigniewItem Proces starzenie Indian Maja ze wsi Yaxcaba (Meksyk) oceniony metodą mikroelektroforezy wewnątrzkomórkowej – EMN(Tower Press Sopot, 2006) Czapla, ZbigniewThe method of intracellular microelectrophoresis in the form of EMN (Electrophoretic Mobility of Cell Nuclei) index can assess well the biological process of human aging in the course of ontogenesis. The aim of this study is to present an application of EMN index as a measure of the biological process of human aging in Maja Indian population from Yaxcaba village (Yucatan, Mexico). The percentage of EMN index is calculated on the basis of the number of epithelial cells with mobile nuclei in reference to the cells with immobile nuclei per 100 cells counted by the researcher. Electrophoresis is performed using a special Biotest apparatus. In the examined (439 females and 337 males) a marked decrease of average values of EMN index was observed. Lower mean EMN value in females is observed. Confirmation of these negative tendency are the simple regression lines in the stable and involutional phases of the ontogenesis for males and females. The EMN index correlate negative with age (statistically significant p0,01) for males r = -0,28 and for females r = -0,35. It follows that the EMN index is a good criterion for assessment in biological process of aging (assessment of biological age). The collected material needs further studies.Item Przyczyny zgonów kobiet i mężczyzn w latach 2000-2005 na przykładzie powiatu gnieźnieńskiego w województwie wielkopolskim(Kieleckie Towarzystwo Naukowe, 2010) Czapla, Zbigniew; Mróz, Anna; Skrzypczak, MagdalenaThe aging of the societies is one of the crucial problems of the present world. In developed countries the proportions of older people are still dramatically increasing. The process of society aging is becoming one of the main socio-economic problem for these countries associated with care of the elderly and pressure on the medical services. Reproductiveness, mortality and migrations exercise significant influence on this complex process. Mortality is particularly important for the reason if this work. The main aim of the present study was the analysis of women and men death causes in Gniezno district (Wielkopolska province). The material contains of the statistical data from 2000 to 2005 years. In the conducted analysis the information about causes of death rate, sex and age were used. The statistical analysis examined: 1) changes in the frequency of total deaths rates of women and men due to analyzed causes, 2) the death rates in the age categories, as well as 3) the trend of changes of frequency death rates in diseases categories, in 2000-2005 years, in Gniezno district. The causes of death rates were provide according to the X the Revision of International Classification of Diseases (ICD-10) valid in Poland from the 1. January 1997. The most frequent causes of deaths of the women and men in Gniezno district were: the cardiovascular diseases and tumors as well as two different causes of death, described according to categorization the ICD-10 as "symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified" as well as "external causes of mortality".Item Stan psychofizyczny człowieka w terminalnej fazie życia(Tower Press Sopot, 2006) Czapla, Zbigniew; Łasiński, DariuszIt is difficult to determine the moment of oncoming death. This study attempts to find a relationship between occurrence and the intensity of selected biological, physiological and psychical traits and oncoming moment of death. Statistical analysis of the obtained results showed a relationship between psychophysical state of examined patients and time of their stay at palliative department. The evaluation of danger of bedsores appearance (EDAB) was used as an indicator of the approach to the moment of death. EDAB is a composed trait including five additive features – 1 – general state, 2 – psychical state, 3 – activity, 4 – ability of moving, 5 – the action of sphincters. Each feature was assessed in a four – point scale. The particular components of EDAB as well as their intensity show that the better biological and psychical state of the patients at the moment of their hospitalization (positive gradient from 1 to 4), the longer time of their stay at palliative department. These results were confirmed by a variance analysis of the total EDAB points conducted with regard to the first day of hospitalization and the last day of investigation (before death) – difference statistically significant. Other features, like swellings, state of nutrition and physical activity also had statistically significant influence on the patients’ time of stay at palliative ward. The study also shows that area of bedsores, sweating and other features (estimated every day) increased along with approaching to the patients' death. These features may be helpful in prediction of the moment of death. In future, more individuals of both sexes need to be studied and more thorough statistical analyses should be applied for better characterization of biological, physiological and psychical features affecting the moment of death at palliative departments.Item The appraisal of the scope for the application of nuclear magnetic resonance (NMR) measurement methods for the estimation of the biological age in various stages of human ontogeny(Adam Mickiewicz University, Faculty of Biology, 1999) Czapla, Zbigniew; Fojud, ZbigniewThe main objective of the study is to find a new physical parameter meeting the criterion of the biological age estimation in various stages of human ontogeny, and thus to find a new research methodology for this field of research. For this purpose an NMR Bruker 200 MHz spectrometer was used. Two physical parameters: relaxation time (T1) and spectrum shape were determined. The research material was oral mucosa epithelium sampled in a group of young people of both sexes (31 subjects) and in a group of men (18 subjects). Relaxation time (T1) and spectrum shape were recorded for hydrogen nuclei (H1). The physical phenomena were analysed statistically (regression analysis) and their biological interpretation was attempted.Item The crania from modern cemeteries in Jaksice (Kujawsko-Pomorskie Province, Poland) and craniometric relationships among medieval and modern Central European populations(2006) Piontek, Janusz; Iwanek, Beata; Czapla, ZbigniewThe paper presents the anthropometric characteristics of the crania from church cemeteries in Jaksice (Kujawy, Poland). The archaeological excavations in Jaksice were carried out in 1968 and 1969. The crania found were dated to the 15th and 17th centuries. For each cranium 10 anthropometric measurements were taken according to R. Martin’s (1928) technique. Their sex and age were estimated according to the methods recommended by European anthropologists. Data on craniological traits for 21 populations from Poland were collected from literature. Using principal components analysis differentiation of the Late Middle Ages and modern populations from Poland was analysed. The analysis was performed also with the use of the biological distance and the cluster analysis methods. High degree of resemblance of the studied crania to the crania of Central Poland (Kujawy, Wielkopolska) populations was revealed.Item The phaseness of human biological development assesse with the use of selected physicochemical methods(Adam Mickiewicz University Faculty of Biology, 2000) Czapla, ZbigniewThe principal idea of the work was to show a new, original method of description of the phenomena of human biological development with the use of nonstandard research methods so far unused in the ontogenetic studies in regard to the stable and involutional phases of ontogenesis. The main purpose of the work was to assess with selected methods individual reactions of a human organism in ontogenesis against the development of the population. Two research methods were selected. They were subsequently used to show individual reactions of a single human organism against the phenotypic variability characterising the population. The research methods employed are based on the physical and chemical properties of biological cells (the Electrophoretic Mobility of Cell Nuclei (EMN) method) as well as on the physical properties of selected physical parameters describing the properties of biological structures (the Nuclear Magnetic Resonance (NMR) spectroscopy method). One of the objectives of the study was to corroborate the applicability of the EMN index method as an adequate criterion 1 A summary of the thesis submitted for the degree of Doctor of Sciences in Adam Mickiewicz University, Poznañ 1999. Professor conferring the degree: Joachim Cie lik. The title of the thesis: The phaseness of human biological development assessed with the use of selected physicochemical methods . 136 Z. Czapla of biological age estimation in each phase of ontogenesis. High sensitivity of the EMN index made it possible to check to what extent a reaction of an individual, resulting from the operation of selected factors increasing the risk of premature death (nicotinism, alcoholism), would permit to assess the deviation of this individual organism from the theoretical course of its ontogenesis determined with the EMN method. Another task under the study involved checking to what degree the ontogenetic development curve in selected subject groups (alcoholics, smokers and non-smokers) determined with the EMN method deviated from the control curve. The principal research tasks regarding the methods of the Nuclear Magnetic Resonance spectroscopy involved attempts to find a new physical parameter, which could serve as a measure of the advancement of certain biological processes accompanying human ontogenesis. In other words an attempt was made to find a physical parameter which could become a new criterion of human biological age estimation regardless of the phase of ontogenesis.Item Zagrożenia dla zdrowia człowieka w warunkach wysokogórskich - fizjologiczne mechanizmy przystosowawcze(Wydawnictwo Naukowe UAM, 2009) Czapla, ZbigniewAccording to the World Health Organization about 140 million people live permanently at altitude higher than 2500 metres above sea level. Man who was born and have been growing up on lowlands was able to adapt to height 5400 metres above sea level for a short time. The main reason of bad functioning of man at high altitude is low pressure of oxygen. Additional factors which are risk for health are: cold, dehydration and intense solar radiation. The consequence of these disturbances are symptoms described like as high-altitude illness (sickness), frostbite appeare very often too. The people which move quickly to high altitudes such as mountaineers and trekkers are exposed to the risk of high-altitude illness. There are two main forms of this sickness: acute mountain sickness and chronic mountain sickness so-called Monga’e disease. The symptoms of acute mountain sickness are headache, nausea, anorexia, insomnia, fatigue, lassitude, vomiting, dizziness, weakness, rapidly increase tiredness and neurological disturbances of physical coordination, impairment of memory and disorientation. The changeable mood and excitement are observed. The symptoms of acute mountain sickness are largely like Chronic mountain sickness is related with increase of erythrocyte number, hypertension of pulmonary circulation and hypertrophy of right ventricle of the heart. This sickness concern the people which are not able adapt to hypoxia in spite of spending the long time in high mountain. Characteristic features of this sickness are cardiac insufficiency, blueness of lips and nails and club-shaped fingers. This form of high-altitude illness finished death often leads to death. When the mechanisms of adaptation to high mountain conditions are insufficient, the pathophysiological processes will lead to high altitude pulmonary edema and high altitude cerebral edema. Apart from symptoms of mountain sickness in case of high altitude pulmonary edema appeared dyspnoea, cough, cyanosis, fever, a rise of pulse and a rise of breathing rating. The symptoms of high altitude cerebral edema are ataxy, nausea, vomiting, changes of behavior, disorientation, mental retardness, visual and/or auditory hallucinations, impairment of vision, convulsions and coma.Item Zastosowanie metod pomiarowych MRJ do określania wieku biologicznego w każdej fazie ontogenezy(Instytut Fizyki Jądrowej im. H. Niewodniczańskiego w Krakowie, 1998) Czapla, Zbigniew; Fojud, Zbigniew